New targets for mucosal healing and therapy in inflammatory bowel diseases
نویسندگان
چکیده
منابع مشابه
Current and Future Targets for Mucosal Healing in Inflammatory Bowel Disease.
The induction and subsequent maintenance of mucosal healing has emerged as one of the central therapeutic goals in the management of patients with inflammatory bowel disease (IBD) (Crohn's disease and ulcerative colitis). Current and novel treatment options are assessed regarding their therapeutic efficacy on the basis of their ability to induce mucosal healing. However, there is still substant...
متن کاملAssessment of mucosal healing in inflammatory bowel disease: review.
BACKGROUND AND AIMS Mucosal healing is an important treatment end-point in inflammatory bowel disease, and achieving mucosal healing has been demonstrated to improve disease-related outcomes. Considerable uncertainty exists, however, regarding the optimal approach for the assessment of mucosal healing. AIMS To compare currently available diagnostic tools for the assessment of mucosal healing ...
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BACKGROUND Endoscopy is an essential diagnostic and therapeutic modality in the clinical care of inflammatory bowel disease (IBD) patients. Endoscopic therapy can be used for treatment of disease-related strictures, surveillance and resection of intraepithelial neoplasia, and treatment of fistulas or disease-related complications, and is currently being evaluated regarding its capacity in in vi...
متن کاملinflammatory bowel diseases, new comments in diagnosis and treatment
ulcerative colitis (uc) and crohn's disease (cd) are chronic inflammatory bowel diseases with uncertain etiology thought to be triggered by interactions between various environmental, genetic and immunologic factors. incidence rate of cd and uc is different in various geographic areas around the world, between 0.1-11 and 0.5-24.5 per 100,000 people for cd and uc, respectively. recent studies in...
متن کاملInflammatory bowel diseases: emerging therapies and promising molecular targets.
An enormous amount of pathoetiologic information continues to accrue from animal models of inflammatory bowel disease and study of the gut microbiome that is providing expanded insight into the causes and mechanisms of inflammatory bowel diseases. This knowledge is being translated into new therapeutics that are being tested in Crohn's and ulcerative colitis patients with an aim to enhance trea...
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ژورنال
عنوان ژورنال: Mucosal Immunology
سال: 2013
ISSN: 1933-0219,1935-3456
DOI: 10.1038/mi.2013.73